Extracellular Vesicles (EVs) from the Tissue Interstitial Fluid represent a new class of information for biomarker discovery, treatment response analysis, and biodistribution studies
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Extracellular Vesicles from the Tissue Microenvironment
Targeted EVs
Capture EVs at their origin
The Targeted Bioscience Interstitial Fluid Collection Kit enables the investigator to sample the in vivo interstitial fluid (IF) without affecting the viability or morphology of the tissue cells. It is a one-step method to collect the interstitial fluid from a living tissue section for extracellular vesicle (EV) harvesting.
EVs represent a unique heterogeneous mixture of biological components within the tissue microenvironment.
Interstitial fluid EVs represent a new class of information directly from the cell.
This highly efficient method is reproducible, provides unique molecular information, and unveils new insights not found in cultured cells.
Highly Efficient isolation of the resident interstitial fluid extracellular vesicles from living excised tissue.
The Targeted Bioscience Interstitial Fluid Collection Tube/Kit is optimized to isolate the EVs of all subtypes derived from an excised living tissue biopsy. This kit protects the tissue from damaging centrifugal forces and uses a separation matrix to facilitate tissue vesicular extraction. We observed a highly reproducible enrichment of extracellular vesicles from the interstitial fluid (See Figure A,B9 Tumor IF EVs contain molecular information not present within cultured tumor cell EVs (See Figure C) and reveals previously unknown molecular insights.
Advancing our understanding and treatment of complex diseases through targeted tissue and extracellular profiling
TARGETED EVs
Unlock the Secrets of Extracellular Vesicles from Tissue Interstitial Fluid
Efficient
Excellent recovery of interstitial fluid extracellular vesicles of all subtypes
Flexible
Fully compatible with all EV separation, purification, and characterization methods
Simple
One-step protocol that takes less than 10 minutes to extract IF EVs
Versatile
Suited for all molecular targets, such as RNA, DNA, protein, lipids, and glycolic signatures.
Convenient
Require simple benchtop low-speed centrifuge to complete extraction.
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Seamless
Integrates with standard histological tissue preparation protocols to preserve tissue morphology and viability
Applications
Accurate, cell-specific data for a variety of downstream applications.
Advanced Extracellular Vesicles Isolation Kit: High-Quality Results for Your Research Needs
Our extracellular vesicles isolation kit is an advanced solution for researchers seeking high-quality extracellular vesicles for their experiments. Designed to deliver consistently high yields, the kit is ideal for various downstream applications such as protein analysis, western blotting, and cellular studies. By incorporating a highly efficient isolation method, researchers can achieve purity and precision without compromising sample integrity.
This isolation kit has been rigorously tested to ensure that researchers can rely on it to deliver results that meet the demands of cutting-edge research. Whether working with serum, plasma, or other biological fluids, our kit is compatible with various sample types and volumes. The kit is prepared to handle multiple research scenarios, whether for small-scale experiments or larger studies that require scalability.
Simplified Process for Isolating Extracellular Vesicles with High Yields
Isolating extracellular vesicles from biological samples can often be a time-consuming and error-prone process. Our extracellular vesicles isolation kit simplifies this workflow, offering an efficient and straightforward method to isolate EVs. The process is optimized to reduce interference from contaminants, ensuring that only pure, high-quality EVs are isolated.
The kit is compatible with plasma, serum, and other complex biological samples, making it versatile for researchers across various disciplines. Each component of the kit is meticulously designed, including pre-packed columns that streamline the separation process. The method minimizes the risk of sample loss, making it easier to handle small sample volumes while achieving high yields. Detailed resources, such as instructions and product information sheets, guide researchers through the process, ensuring reproducible results every time.
EV Isolation for Superior Research Performance
When it comes to EV isolation, precision and consistency are paramount. Our extracellular vesicles isolation kit has been engineered to provide both. The robust isolation method ensures that EVs isolated from plasma or serum maintain their structural and functional integrity, ready for immediate use in downstream applications.
With this kit, researchers can isolate extracellular vesicles without interference from proteins or other unwanted particles, making it suitable for applications like gel electrophoresis, western blotting, and advanced imaging techniques. The kit’s compatibility with various volumes allows it to adapt to different experimental setups, whether small-scale pilot studies or larger projects requiring high throughput. Storage solutions are included to preserve the quality of EVs, allowing researchers to store samples for extended periods without compromising integrity.
EVs Isolated with Precision and Consistency
The process of isolating extracellular vesicles has traditionally posed challenges, particularly when working with human plasma or serum. Our isolation kit overcomes these obstacles, providing a reliable solution that ensures high-quality EVs are isolated with precision. This is achieved through a carefully designed method that eliminates contaminants while preserving the functional properties of the vesicles.
Researchers can rely on this kit to isolate EVs that are free from interfering substances, ensuring they are loaded with the molecules required for downstream analyses. The kit also includes resources such as user guides and product sheets, which detail the process and help achieve consistent results. With EVs prepared and ready for use, researchers can confidently move on to advanced stages of their experiments, from protein analysis to imaging.
Overview: Why Choose Our Extracellular Vesicles Isolation Kit?
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Simple and convenient : The kit uses a streamlined process for isolating extracellular vesicles from plasma, serum, or other biological fluids.
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High compatibility : Works with various volumes and is adaptable to multiple experimental needs.
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Comprehensive support : Includes detailed resources such as product information sheets and user guides to ensure researchers can efficiently use the kit.
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Optimized storage : Isolated EVs can be stored long-term without loss of quality, making it easier to manage experimental timelines.
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Validated performance : Years of development and testing ensure this kit meets the needs of modern vesicle research.
Designed for Excellence in Vesicle Research
Our extracellular vesicles isolation kit is tailored for excellence in vesicle research. Whether isolating extracellular vesicles from human samples or preparing them for advanced imaging, this kit provides researchers with the tools needed to excel. The method is highly reproducible, minimizing variability and allowing for consistency in results.
The pre-packed columns are designed to simplify the process while maintaining high performance, even for challenging samples like serum and plasma. Achieved results are further validated by detailed images and figures provided in the accompanying product resources, giving researchers confidence in the performance of the isolation kit.
EV Isolation for Western Blotting, Protein Analysis, and Beyond
Extracellular vesicles isolated using our kit are perfectly suited for downstream applications such as protein analysis, gel electrophoresis, and western blotting. The quality of the EVs ensures reliable and reproducible results, making it an essential tool for advanced research.
Researchers can isolate exosomes and extracellular vesicles loaded with critical molecules, ensuring they are ready for immediate use. This allows for quicker turnaround times and a more efficient research process. With storage solutions provided, the EVs can be safely stored and used as needed, offering flexibility in experimental design.
Tailored for Researchers: Comprehensive Resources Included
The kit is designed with researchers in mind, including detailed product sheets, guides, and references to make the isolation process as straightforward as possible. Pre-packed columns and compatibility with various sample volumes ensure the kit is versatile and easy to use.
Our isolation kit offers everything researchers need to achieve high yields of EVs from plasma or serum samples, saving time and resources. Check our catalog for additional details about sample processing, storage solutions, and more information about this innovative product.