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Extracellular Vesicles from the Living Tissue Microenvironment

A new class of biomarkers for precision medicine.

TARGETED EVs

Capture EVs at their source- within the tissue

The Targeted Bioscience Interstitial Fluid Collection Kit enables the investigator to sample the in vivo interstitial fluid (IF) without affecting the viability or morphology of the tissue cells. It is a one-step method to collect the interstitial fluid from a living tissue section for extracellular vesicle (EV) harvesting.

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EVs represent a unique heterogeneous mixture of biological components within the tissue microenvironment.  Interstitial fluid EVs represent a new class of information directly from the cell.


This highly efficient method is reproducible, provides unique molecular information, and unveils new insights not found in cultured cells. 

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DISCOVER NEW INSIGHTS

Highly Efficient isolation of the resident interstitial fluid extracellular vesicles from living excised tissue

We observed a highly reproducible enrichment of extracellular vesicles from the interstitial fluid (See Left Graphs). Tumor IF EVs contain molecular information not present within cultured tumor cell EVs (See Below Venn Diagrams) and reveals previously unknown molecular insights.

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 Key Features

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Efficient

Excellent recovery of itnerstitial fluid extracellular vesicles of all subtypes

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Simple

One-step protocol that takes less than 10 minutes to extract IF EVs

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Convenient

Require simple bench top low speed centrifuge to complete extraction.

Digital pathology solution is Flexible in its approach
Flexible

Fully compatible with all EV separation, purification, and characterization methods.

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Versatile

Suitable for all molecular targets, such as RNA, DNA, proteins, lipids, and glycolic signatures

Advancing our understanding and treatment of complex diseases through targeted tissue and extracellular profiling

Did you watch our recent webinar?

Watch the webinar to explore the critical role EVs play in cell communication, their potential in diagnostics, and how they can revolutionize therapeutic approaches. Whether you're a seasoned researcher or new to the field, this session offers valuable insights into the latest advancements in EV research. 

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